What is it ?
MUGA is an acronym (short form) for Multi-Gated Acquisition. MUGA was first introduced in the early 1970s and quickly became accepted as the preferred technique for measurement of LVEF with a high degree of accuracy. Several early studies demonstrated an excellent correlation of MUGA-derived LVEF with values obtained by cardiac catheterization contrast ventriculography.

Multi-Gated Acquisition is a form of Ventriculography, which is performed by using radioisotope i.e. Technetium 99m (Tc99m). The RVG is performed by labeling the patient's red blood pool with a radioactive tracer and measuring radioactivity over the anterior chest, with a suitably positioned gamma camera, as the radioactive (labeled) blood flows through the large vessels and heart.